Cell Line Lysates
Cayman Chemical Aszonapyron A 2.5mg
A meroditerpene fungal metabolite with diverse biological activities; inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively); active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation; active against P. falciparum in vitro (IC50 = 1.34 μg/ml)
ABclonal Technology ATF6 Rabbit pAb
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
Genscript Corporation NRG1 Beta 1 hFc ChimeraBiotin
euregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB) and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor which increases the expression of the 2 subunit of the - aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor
Meso Scale Discovery HIF1alpha Whole Cell Lysate
The HIF-1alpha Whole Cell Lysate Kit from Mesoscale Discovery provides reagents to detect HIF-1alpha protein levels in cell lysates The kit contains a 96-well plate coated with capture antibody detection antibody read buffer sample diluent and lyophilized recombinant HIF-1alpha standard to generate a standard curve This immunoassay allows sensitive and accurate measurement of HIF-1alpha levels with as little as 15 g of total protein per well The electrochemiluminescent detection method provides a wide dynamic range and high sensitivity with low background This product enables quantification of HIF-1alpha protein expression in cell lysates for hypoxia and cancer research
ABclonal Technology TMPRSS6 Rabbit pAb
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants.
Abcam Human LTB4R2 (Leukotriene B4 Receptor 2) knockout HeLa cell lysate.
Human LTB4R2 (Leukotriene B4 Receptor 2) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human RNF19B knockout A549 cell lysate.
Human RNF19B knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FAM3C (ILEI) knockout HeLa cell lysate.
Human FAM3C (ILEI) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Biotium Primary Antibody CD9 P21926 CF583R 1/EA
ExoBrite STORM CF583R CD9 Antibody is designed for detection of extracellular vesicles by STORM CF583R has been validated and recommended for STORM microscopy and has Ex/Em at 585/609 nm 500 uL
Abcam Human TRABD (TraB domain containing) knockout HEK-293T cell lysate.
Human TRABD (TraB domain containing) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human SLC39A8 (BIGM103/ZIP8) knockout HeLa cell lysate.
Human SLC39A8 (BIGM103/ZIP8) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical AcVDVADpNAtrIfluoroACTAt 2.5mg
A colorimetric caspase-2 substrate; cleavage of the VDVAD peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of caspase-2 activity; can also be cleaved, with lower efficiency, by caspase-3 and -7
Abcam Human UHMK1 (KIST/KIS) knockout HeLa cell lysate.
Human UHMK1 (KIST/KIS) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Kelch-like ECH-associated protein 1 (KEAP1) | ≥90.0% | 50 UG
Recombinant human Kelch-like ECH-associated protein 1 (KEAP1) produced in Sf9 insect cells with N-terminal His and GST affinity tags. Supplied as a 0.22 μm-filtered solution in 20 mM Tris, 300 mM NaCl, 10% glycerol (pH 7.5), this protein is designed for biochemical and binding assays involving the NRF2-KEAP1 pathway.
- Recombinant full-length human protein expressed in Sf9 insect cells.
- N-terminal His and GST affinity tags for purification and detection.
- Supplied in buffered, filtered solution (20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5).
- Purity ≥90.0% as determined by reducing SDS-PAGE.
- Endotoxin <1 EU/μg by LAL method.
- Apparent molecular weight ~93-109 kDa by SDS-PAGE.
- Store at -80°C for long-term stability; avoid repeated freeze-thaw cycles.